Medications Similar to Semaglutide

Semaglutide is a medication belonging to a class called glucagon-like peptide-1 (GLP-1) receptor agonists. These drugs mimic the effects of a natural hormone called GLP-1, which helps regulate blood sugar and appetite. Several other medications share similar properties and uses with semaglutide, although they may differ in specific details like dosage, administration method, and approved indications.


Here are some examples of medications similar to semaglutide:

1. Liraglutide (Victoza, Saxenda): This GLP-1 agonist is available as both an injection (once daily) and a tablet (once weekly). Like semaglutide, it’s approved for treating type 2 diabetes and, in higher doses, for weight loss.

2. Dulaglutide (Trulicity): This once-weekly injectable medication is approved for treating type 2 diabetes and has similar effects to semaglutide on blood sugar and appetite.

3. Tirzepatide (Mounjaro): This newer GLP-1 agonist is also a dual incretin regulator, meaning it targets both GLP-1 and GIP (glucagon-like peptide-1) receptors. It’s approved for treating type 2 diabetes and shows promising results for weight management.

4. Lixisenatide (Adlyxin): This injectable medication is approved for treating type 2 diabetes and has a shorter duration of action compared to other GLP-1 agonists.

5. Exenatide (Bydureon, Bydureon BCise): This long-acting injectable GLP-1 agonist is used twice weekly for type 2 diabetes management.


It’s important to remember that this information is not a substitute for professional medical advice. If you’re considering taking any medication or IV therapy, it’s crucial to consult your OWCP doctor to discuss your specific needs and determine the best option for you. They can help you understand the potential benefits and risks of each medication and ensure it aligns with your overall treatment plan.